Stefano Spiezia

Does nsPFA actually last? Until now, that question didn't have a real answer. In this episode, Professor Stefano Spiezia joins Jennifer Holkem to break down the 22-month durability data on nsPFA — non-thermal pulsed field ablation for thyroid nodules — presented at the 2026 NASIT meeting in Portland. Professor Spiezia is head of the Division of Endocrine and Ultrasound Guided Surgery at the Sea Hospital in Naples, Italy, and conducted the first-in-human feasibility study of nsPFA for thyroid nodules. He's also director of the Save Your Thyroid International School for Interventional Thyroid Procedures. In this episode, they cover: ✅ The 22-month durability data: zero nodule regrowth, 74% average volume reduction, and no serious adverse events ✅ How nsPFA works differently from RFA and microwave ablation — a non-thermal mechanism that triggers regulated cell death instead of burning tissue ✅ Why nsPFA nodules kept shrinking over time instead of plateauing, unlike thermal ablat…